Name | sodium 5-oxo-L-prolinate |
Synonyms | L-PCA-NA 249-277-1 Sodium PCA Sodium L-Pyroglutamate sodium l-pyroglutamate sodium 5-oxo-L-prolinate Sodium Pyrrolidone Carboxylate 5-Oxo-L-proline monosodium salt Sodium (2S)-5-oxopyrrolidine-2-carboxylate sodium (2S)-5-oxo-2-pyrrolidinecarboxylate l-pyrrolidone-5-carboxylic acid sodium salt |
CAS | 28874-51-3 |
EINECS | 249-277-1 |
InChI | InChI=1/C5H7NO3.Na/c7-4-2-1-3(6-4)5(8)9;/h3H,1-2H2,(H,6,7)(H,8,9);/q;+1/p-1/t3-;/m0./s1 |
Molecular Formula | C5H6NNaO3 |
Molar Mass | 151.1 |
Density | 1.45 |
Melting Point | 125°C |
Boling Point | 313.7℃[at 101 325 Pa] |
Flash Point | 227.8°C |
Water Solubility | 613g/L at 20℃ |
Solubility | Methanol (Sparingly), Water |
Vapor Presure | 5.4hPa at 20℃ |
Appearance | Pale yellow transparent liquid |
Color | Clear Colorless to Pale Yellow |
pKa | 9.94[at 20 ℃] |
Storage Condition | Refrigerator |
Reference Show more | 1. Li, Shili, et al. "Evaluation of the antibacterial effects and mechanism of action of protocatechualdehyde against Ralstonia solanacearum." Molecules 21.6 (2016): 754.https://doi.org/10.3390/molecules21060754 |
sodium PCA | sodium PCA, also known as sodium pyrrolidone carboxylate, is used as moisturizer, skin conditioner and antistatic agent in cosmetics. it is a natural ingredient of skin and a good moisturizer. It has the function of strengthening cutin and is used to enhance the skin's own moisturizing ability. Sodium PCA (SodiumPCA) is a humectant naturally occurring in human skin. It is the main component of the stratum corneum of the skin. It has strong moisturizing properties and is an amino acid derivative. PCA sodium has a high water absorption capacity, can absorb water from the air, and hyaluronic acid (H · A) hyaluronic acid (H · A) hygroscopicity, and is much stronger than glycerin, propylene glycol, sorbitol and other humectants. It is a transparent, colorless, odorless and slightly salty liquid. It can combine water with cells and grasp water several times its own weight. Sodium PCA delivers moisture to hair and skin and is used as an emollient or moisturizer in hair conditioners and moisturizers; it can also be seen in shampoos, hair sprays, hair sprays, skin fragrances and various other hair and skin. The CIR approved PCA sodium concentration limit is 4%. The PCA-Na is soluble in water. Slightly soluble in organic solvents, at the same temperature and concentration, its viscosity is much lower than other humectants, does not have the sticky and heavy feeling of glycerin, and has high safety, and has almost no irritation to the skin and eye mucosa. Other moisturizers have good synergy, and they have good effects when mixed. |
Sodium glutamate | Sodium glutamate is a sodium salt of amino acid glutamic acid. It is an odorless and colorless crystal that disintegrates and melts at 232°C. Sodium glutamate has good water solubility and can dissolve 74 grams of sodium glutamate in 100 ml of water. The main function of MSG is to increase the umami taste of food. It is most used in Chinese cuisine and can also be used in soups and sauces. MSG was discovered and patented by Japan's Ajinomin (Ajinomin) Company in 1909. The appearance of pure monosodium glutamate is a white crystalline powder. When monosodium glutamate is dissolved in water (or saliva), it will quickly ionize into free sodium ions and glutamate ions (glutamate ions are anions of glutamate, and glutamate is a natural amino acid). It should be noted that if monosodium glutamate is used at a high temperature above 100 ℃, sodium glutamate will be converted into sodium pyroglutamate, which is carcinogenic to human body. And if in an alkaline environment, MSG will react chemically to produce a substance called disodium glutamate. Therefore, it should be used and stored properly. MSG is a kind of seasoning, the main ingredient is sodium glutamate. It should be noted that if monosodium glutamate is used at a high temperature above 100 ℃, sodium glutamate will be converted into sodium pyroglutamate, which is carcinogenic to human body. And if in an alkaline environment, MSG will react chemically to produce a substance called disodium glutamate. Therefore, it should be used and stored properly. Excessive intake may lead to gastric cancer and other human visceral diseases. Normal consumption of sodium pyroglutamate is harmless to the human body, including as a food additive (ie oral). Normal use of sodium pyroglutamate is harmless to the human body, including as a skin care product (I. e. skin penetration). However, there are reports in the literature that if pyroglutamate is directly injected into the brain of mice, it will produce neurotoxicity. However, there are no reports of pyroglutamic acid in the human brain. |